Insomnia is a major complaint from patients with huge personal and economic costs. Some 50 to 70 million adults display some form of sleeping disorder, with men reporting a higher rate of insomnia than women according to some studies.90% of people who suffer from depression also experience insomnia. Many drugs may affect the quality and duration of sleep. If you are struggling with insomnia and take one of these medications, talk to your doctor and see whether your medications are not the reason for your sleepless nights.
Here is a list of medications that we found in studies to be adversely effecting sleep.
- Prednisone. A steroid given for asthma or COPD, hives, and other skin conditions, prednisone has been shown to disrupt your sleep.
- Sertraline (Zoloft). Studies show sertraline is a significant disruptor of sleep. Sertraline is a selective serotonin reuptake inhibitor (SSRI) prescribed for depression and obsessive compulsive disorder.
- Paroxetine (Paxil). An SSRI used for anxiety, depression, and OCD, studies reveal that paroxetine significantly affects sleep.
- Fluoxetine (Prozac). Another well known SSRI used for depression, panic disorder, OCD, and premenstrual dysphoric disorder, fluoxetine has also been shown in studies to contribute to insomnia.
- Citalopram (Celexa). Another SSRI that may disrupt sleep.
- Fluvoxamine (Luvox). Yet another old school SSRI, this antidepressant may disrupt your sleep.
- Donepezil (Aricept). Donepezil is indicated for the treatment of dementia, specifically Alzheimer’s, and may cause disrupted sleep in folks taking it.
- Venlafaxine (Effexor). Slightly different from SSRIs, this SNRI (serotonin, norepinephrine reuptake inhibitor) is prescribed for generalized anxiety disorder and depression. Studies show it significantly contributes to insomnia.
- Pramipexole (Mirapex and Mirapex ER). These medications are used for restless leg syndrome (RLS) and Parkinson’s disease. Studies show they may contribute to sleep disturbance.
- Rotigotine (Neupro). Neupro is a brand-name-only patch prescribed for restless leg syndrome and Parkinson’s disease, and it may cause insomnia.
- Ropinirole (Requip). Another medication used for the treatment of restless leg syndrome, ropinirole may contribute to insomnia.
- Varenicline (Chantix). Prescribed for folks who want to quit smoking, studies reveal that Chantix may disrupt your sleep.
- Rivastigmine (Exelon). This patch is used for the treatment of dementia and has been shown in studies to affect sleep.
- Naltrexone (Revia). Naltrexone is an opioid receptor antagonist used for alcohol dependence. It’s also part of the new weight loss medication Contrave (a combination of naltrexone and bupropion). Naltrexone can negatively affect sleep.
- Olanzapine (Zyprexa). Olanzapine is used for bipolar disorder and psychosis associated with dementia and studies show it may contribute to insomnia.
- Levodopa. Part of Sinemet (a combination of levodopa and carbidopa), it’s used for restless leg syndrome as well as Parkinson’s disease and may cause insomnia.
- Amantadine (Symmetrel). Amantadine is an antiviral medication that also happens to be used for Parkinson’s disease and schizophrenia, and it may negatively impact sleep.
- Cabergoline (Dostinex). Cabergoline is a medication that’s effective both for restless leg syndrome and for lowering levels of prolactin in those with prolactin-producing pituitary tumors. Studies show cabergoline may cause insomnia.
Original article published by GoodRx